The role of surgical skin grafting in pyoderma gangrenosum

Authors

  • Zane Attard Department of Dermatology, Mater Dei Hospital, Msida, Malta Author
  • Bettina Booker Department of Dermatology, Mater Dei Hospital, Msida, Malta Author
  • David Borg Department of Plastic Surgery, Mater Dei Hospital, Msida, Malta Author
  • Daniel Micallef Department of Dermatology, Mater Dei Hospital, Msida, Malta Author
  • Lawrence Scerri Department of Dermatology, Mater Dei Hospital, Msida, Malta Author
  • Duncan Aquilina Department of Plastic Surgery, Mater Dei Hospital, Msida, Malta Author

DOI:

https://doi.org/10.25251/eh2cnd59

Keywords:

pyoderma gangrenosum, skin grafting, skin surgery

References

1. Ghode DB, Hirani S, Kenjale S, et al. Pyoderma gangrenosum: a challenging cutaneous manifestation in dubowitz syndrome. Cureus. 2023;15(8):e43408. doi:10.7759/cureus.43408. PMID:37706150

2. Shen J, Zhang W, Jiang X. Pyoderma gangrenosum after cesarean section treated with skin graft: A case report. Medicine (Baltimore). 2019;98(18):e15380. doi:10.1097/MD.0000000000015380. PMID:31045786

3. Guliyeva G, Janis JE. Postsurgical pyoderma gangrenosum requiring plastic surgical intervention: a practical review. Plast Reconstr Surg Glob Open. 2024;12(1):e5505. doi:10.1097/GOX.0000000000005505. PMID:38250211

4. Morgenstjerne-Schwenck LET, Knudsen JT, Prasad SC. Efficacy and safety of skin grafting in treatment of vasculitic ulcer and pyoderma gangrenosum-A systematic review. Wound Repair Regen. 2021;29(2):240-253. doi:10.1111/wrr.12882. PMID:33377584

5. Eisendle K, Thuile T, Deluca J, Pichler M. Surgical treatment of pyoderma gangrenosum with negative pressure wound therapy and skin grafting, including xenografts: personal experience and comprehensive review on 161 cases. Adv Wound Care (New Rochelle). 2020;9(7):405-425. doi:10.1089/wound.2020.1160. PMID:32320362

6. Pichler M, Larcher L, Holzer M, et al. Surgical treatment of pyoderma gangrenosum with negative pressure wound therapy and split thickness skin grafting under adequate immunosuppression is a valuable treatment option: Case series of 15 patients. J Am Acad Dermatol. 2016;74(4):760-765. doi:10.1016/j.jaad.2015.09.009. PMID:26979359

7. Maronese CA, Pimentel MA, Li MM, et al. Pyoderma gangrenosum: an updated literature review on established and emerging pharmacological treatments. Am J Clin Dermatol. 2022;23(5):615-634. doi:10.1007/s40257-022-00699-8. PMID:35606650

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Published

03/02/2026

Data Availability Statement

The data that support the findings of this case report are available from the corresponding author upon reasonable request.

Issue

Vol. 32 No. 1 (2026): Dermatology Online Journal

Section

Letter

License

Copyright (c) 2026 Zane Attard, Bettina Booker, David Borg, Daniel Micallef, Lawrence Scerri, Duncan Aquilina (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.