Pancreatic panniculitis: A rare manifestation of post-endoscopicretrograde cholangiopancreatography hyperamylasemia

Authors

  • Zane Attard Department of Dermatology, Mater Dei Hospital, Msida, Malta Author
  • Stephanie Farrugia Department of Dermatology, Mater Dei Hospital, Msida, Malta Author
  • Eliezer Zahra Bianco Department of Gastroenterology, Mater Dei Hospital, Msida Malta Author
  • David Pisani Department of Pathology, Mater Dei Hospital, Msida Malta Author
  • Liam Mercieca Department of Gastroenterology, Mater Dei Hospital, Msida Malta Author
  • James Pocock Department of Gastroenterology, Mater Dei Hospital, Msida Malta Author

DOI:

https://doi.org/10.25251/va2ter89

Keywords:

pancreatic panniculitis, systemic disease

Abstract

Pancreatic panniculitis is a rare cutaneous manifestation affecting patients with pancreatic disease. This eruption is associated with acute pancreatitis, pancreatic malignancies, pancreatic pseudocysts, post–endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis, and pancreatic trauma. Increased efflux of pancreatic enzymes from the diseased pancreas appears to cause extra-abdominal fat necrosis and may manifest in the skin. We report a 59-year-old woman with cutaneous pancreatic panniculitis presenting after ERCP with elevated amylase levels but no symptoms of pancreatitis.

References

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Published

03/02/2026

Data Availability Statement

All relevant data may be made available by the corresponding author upon reasonable request.

Issue

Vol. 32 No. 1 (2026): Dermatology Online Journal

Section

Photo Vignette

License

Copyright (c) 2026 Zane Attard, Stephanie Farrugia, Eliezer Zahra Bianco, David Pisani, Liam Mercieca, James Pocock (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.